CLOSE

DCGI okays AstraZeneca drug for treatment of heart failure in adults

DCGI approves AstraZeneca (images: Envato Elements, Pngtree)

The Drugs Controller General of India (DCGI) on July 24 granted extended indication approval to AstraZeneca India's Dapagliflozin in the treatment of heart failure in adults.

Dapagliflozin is already approved for heart failure patients with reduced ejection fraction. The additional indication will expand the indication for all types of heart failure irrespective of ejection fraction, the company said in a statement.

Fight against heart failure in India

Heart failure is a chronic, progressive disease affecting nearly 64 million people globally and about 10 million in India, and includes both heart failure with preserved ejection fraction and reduced ejection fraction.

The heart's ejection fraction refers to the amount or percentage of blood pumped (or ejected) out of the heart's left ventricle with each contraction. The approval is based on the results from the Phase III trial in 6,263 randomized patients with left ventricular ejection fraction greater than 40%, with or without type-2 diabetes.

The trial showed Dapagliflozin is the only SGLT-2i with mortality benefits in the analysis of heart failure across left ventricular ejection fraction (LVEF). significantly reduced the composite of cardiovascular (CV) death or worsening heart failure in patients with HF with mildly reduced or preserved ejection fraction (EF), compared to placebo.

The available data from Indian heart failure registries show that they are younger by 10 years, and the majority of the burden lies below 65 years of age, as compared to the patients from high-income countries.

(Source: IANS)

Edited for style

For more such updates and news on the go, follow us on

Instagram | YouTube | Facebook

Comments

Post a Comment

Popular posts from this blog

Know what is the difference between Weight Loss and Fat Loss? Somewhere you are also not making this mistake

Image
Image Source: Freepik Ahmedabad. 04 September 2023 Monday Obesity is becoming a big problem nowadays. People are falling prey to obesity due to bad diet and lifestyle. Sitting in the same place continuously in the office or at home also starts accumulating fat in the body. However, most of the people are becoming very aware about this and also want to stay fit. People use different methods to control their weight. But maintaining a healthy weight is also necessary to keep the body fully healthy and at the same time it is very important to know whether you should lose weight or lose fat to maintain a healthy weight. In general, it is not good to just lose weight because the entire body weight is lost in the process of muscle, water, glycogen and fat. Fat loss involves reducing body fat already stored in the body. So it is considered as a better option. What is weight loss? Weight loss simply means to lose body weight, it means to lose muscle, fat and water weight from the body. M...
Read more

Mint is very beneficial for health, it eliminates these 5 diseases

Image
Image Envato Dt. 19 May 2023, Friday Mint is much loved in the heat due to its cooling properties. The scent of mint makes people feel refreshed. Mint leaves can be used both green and dry. And it can be used in food and drink. It is also used in some cold drinks. Some of us like to put mint in tea. Mint is very beneficial for health. According to the research, many diseases can be relieved in the body by consuming mint. Today let's learn about five benefits of mint. Provides relief from irritable bowel syndrome Consuming mint can provide relief from irritable bowel syndrome (IBS). According to medical reports, this syndrome causes abdominal pain, gas, bloating and digestive problems. Research has found that consuming mint can provide relief from these ailments. It contains an ingredient called menthol. This relaxes the musculature of the digestive system. The problem of indigestion is removed Mint relieves indigestion, an indigestion problem that occurs when food takes too ...
Read more

In these diseases, the patient should not eat bananas by mistake, otherwise you will be in trouble!

Image
Image Source: Freepik Ahmedabad. 23 September 2023 Saturday Bananas are rich in iron and calcium. People like to eat it from fasting to breakfast but this does not mean at all that you can eat the fruit anytime and it will be beneficial. Eating more bananas causes stomach upset. So bananas should be eaten carefully as it dehydrates your stomach and slows down the metabolic rate. This can cause constipation problem. Sometimes eating bananas can be harmful. Meanwhile, the question arises as to which people should not eat bananas. Banana should not be eaten in any disease High blood sugar Diabetic patients can be harmed by eating bananas. Also this can increase your sugar level. Eating bananas can quickly cause a sugar spike and lead to diabetes. So a diabetic patient should not eat bananas. Asthma and bronchitis Eating bananas can cause asthma and bronchitis. Bananas can aggravate your allergies and will take a long time to recover from. So if you are suffering from asthma and br...
Read more

Massaging the soles of the feet in this way will relieve fatigue, insomnia and eyes

Image
Image Envato Dt. 18 February 2023, Saturday In childhood, mothers, grandmothers or children used to massage the soles of their feet before going to bed at night. In fact massage is very important in Ayurveda. Know the benefits of foot massage and the correct way to massage. We all massage the head and hands and feet, but did you know that massaging the soles of the feet also has many benefits. Massaging the soles of the feet relieves tiredness, insomnia, stress throughout the day and also provides restful sleep. Not only this, the lighting of the eyes also remains good. Foot massage is considered very important in our Ayurveda. If you regularly massage the soles of your feet while sleeping at night, it will refresh you throughout the day and keep away from many diseases. Ayurvedic expert Rai An Ayurvedic massage therapist has given detailed information about massaging the soles of the feet on social media and said that padabhyanga i.e. foot massage can cure gas problems. Not only...
Read more

If you also sleep late, be careful, otherwise this problem may occur

Image
Oversleeping Side Effects: Our elders used to advise us to get up before sunrise i.e. Brahma Muhurta. But our current lifestyle is such that it is not easy for many people to do this. But people who sleep late at night and wake up late may face these serious problems. Sleeping for long hours can make your body vulnerable to many diseases. Its 5 disadvantages are very dangerous… Obesity People who are in the habit of sleeping and staying up late have a very low metabolic rate. This makes it difficult to burn calories after eating anything. Due to which fat starts accumulating in the body and obesity can increase due to this. Mental health will deteriorate People who sleep late in the morning can have a bad effect on their mental health. According to health experts, people who do this can develop problems like irritability, depression and mood swings, which can have serious consequences. Digestive problems Sleeping late in the morning has a bad effect on the digestive system. Thi...
Read more

Artificial sugar is like sweet poison, excessive consumption will cause diabetes risk: WHO warning

Image
Image Envato Dt. 17 April 2023, Wednesday Nowadays our life style has changed, or it is not wrong to say that the life style of most people is getting worse. Now the physical work like before is less. Due to which people become big. And after that, various diseases take hold in the body in which problems like diabetes and hypertension start to occur. Artificial sugar is not a true substitute for sugar But now we should try to improve it. For that, regular practice of yoga, exercise, meditation etc. should be done daily. And at the same time one should be careful in eating and drinking. In which the use of artificial sugar should be especially avoided. It is like a sweet poison. It does not increase the calories in the body but the question is whether artificial sugar is the right substitute for sugar. But using it is not the right option. WHO warning WHO has warned about this and said that you are advised that the use of non-sugar sweeteners or artificial sugars that people are ...
Read more

High blood pressure patient should consume these 3 fruits, BP will be under control

Image
Image Source: Freepik Ahmedabad. 15 July 2023 Saturday Nowadays due to changing life style people have to face many problems which are caused due to food and drink, change in daily routine, lack of exercise etc. which sometimes become fatal disease for us. Like cancer, diabetes, obesity etc. High blood pressure is a life-long disease that requires a lot of sacrifice, and if left unchecked, it can be life-threatening, leading to brain hemorrhage, paralysis, and more. So it is very important to be careful. Control blood pressure by eating these fruits 1. Banana Banana is a year-round fruit that is very nutritious. This strengthens digestion. Nutrients found in bananas work as a panacea in blood pressure, consuming it daily keeps blood pressure under control and also helps protect you from stroke. 2. Kiwi Kiwi is a very nutritional fruit that contains many nutrients that are beneficial for health. It is rich in antioxidants and minerals that keep the digestive system strong. Apar...
Read more

Corona has increased the tension again! Entry of new variants in Europe, experts advise to be cautious

Image
Corona virus cases have been a cause of global concern for more than three years. The number of new infections has improved significantly over the past few months, but the latest report may raise concerns again. The Center for Disease Control and Prevention has found cases of the new sub-variant EU.1.1 of Corona in the North-Western states of America. Recently, this variant has been found to be the main cause in many patients with confirmed infections. All countries need to be vigilant about Corona According to health experts, research is being done continuously to know about this variant. Currently, about 1.7% of COVID-19 cases in the United States are caused by this variant. Also in Montana and Colorado in the US, this variant is found to be the major cause of 8.7% of cases. Health experts have warned that all countries need to be vigilant about Corona. A new sub-variant of Corona EU.1.1 Preliminary research so far has revealed that this new sub-variant EU.1.1 is basically a pro...
Read more

What does OD-BD-TDS mean on a doctor's prescription? Everyone should know about it, know different codewords

Image
Image Envato Dt. 15 April 2023, Monday Everyone will get sick sometimes, in which many people buy medicine from medical for minor and major ailments. But sometimes if there is more trouble, one has to go to the doctor. But really it is necessary to consult a doctor in case of minor or major illness. Many of us must have gone to the doctor but we do not pay much attention to what the doctor prescribes because it is not our subject. In which the doctor properly examines the patient and writes the code word about his medicine in his prescription. Although the doctor tries to ensure that the patient understands the dosage of the medicine correctly, it is very difficult to understand this language of the doctor. As they have words like BID and BD written in them most of the people do not know what this means. But today we know such a codeword. In Latin 'BID' means bis in die twice a day. Doctors only prescribe BID In fact the food codes that are written before medicine are ofte...
Read more

Varicose Veins: Risk of this major disease by standing or sitting for a long time, know how to avoid it

Image
Image Source: Freepik Ahmedabad. 26 October 2023 Thursday People who work sitting or standing for a long time suffer from leg pain. Along with this, a change also starts happening in his body, about which he does not even realize. If this is not taken care of for a long time, the problem may increase and the body may suffer a lot of damage. The veins on the body are swollen You may have noticed at times that many people have more varicose veins than others. Especially in their muscles, upper part of the palm, chest, knees and other parts of the body are also seen in this vein. Varicose veins are called varicose veins. These changes seen in the veins indicate an illness. Causes of Varicose Veins Wearing too tight jeans Obesity Constant changes in blood pressure Food reaction Sitting in a chair for long periods of time Sitting or standing for long periods of time Reaction to allopathic medicines Treatment of varicose veins Rest your feet every hour while working Laser the...
Read more